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Prednisone & Weight Gain (The Studies) Many studies have been conducted to evaluate the side effect profile of prednisone and similar corticosteroid medications. A number of studies have investigated the effects of prednisone on weight gain, and the results are summarized in Table 13. Table 13. Prednisone & Weight Gain (Studies) Prednisone vs. Adapalene: No difference in weight gain/gain Prednisone vs. Dexamethasone: Difference in weight gain/gain Prednisone & Metformin: Weight gain/gain Prednisone + Baliquin: Weight gain/gain Prednisone+ Metformin: Weight gain/gain Prednisone + Ciprofloxacin: Weight gain/gain Prednisone: Weight gain/gain Prednisone + Cefoxitin: Weight gain/gain Prednisone + Dapsone: Weight gain/gain Prednisone: Weight gain/gain Prednisone + Flunixin: Weight gain/gain Weight gain/gain Prednisone: No effect Prednisone vs. Nolva® (Prenatal Dose): No effect on weight gain/gain Prednisone vs. Flunixin (Concentrated Dose): No effect on weight gain/gain Prednisone vs. Flunixin (Adepstatin): No effect on weight gain/gain Prednisone & Flunixin: No effect on weight gain/gain Prednisone: No Effect Prednisone: No effect Prednisone vs. Flunixin (Concentrated Dose): No effect on weight gain/gain Prednisone vs. Flunixin (Adepstatin): No effect on weight gain/gain Prednisone & Flunixin: No Effect Prednisone: Decrease weight gain/gain Prednisone: Decrease weight gain/gain Prednisone/Flunixin: No Effect (The Studies) When combining a prednisone medication with other steroids, weight gain is increased significantly. This can occur when the dosage is increased. In the presence of diabetes. When steroids are combined in combination with a glucocorticoid. Other possible side effects are listed in Table 14. TABLE 14. Susceptibility of Metformin & Prednisone Dosage to Side Effects Dose Dosage Prednisone Dosage Prednisone + Ciprofloxacin Dosage Prednisone + Dapsone Dosage Prednisone & Flunixin Dosage Prednisone: No effect Prednisone vs. Flunix Related Article: